Sequential Measurement Based Multi-Parameter Microfluidic Flow Cytomolecular Analyser

Key Highlights

This project integrates microfluidic chip technology with flow cytometry and our proprietary MSTS Transfer™ Technology to create a groundbreaking single-laser, 96+ parameter microfluidic flow cytomolecular analyser. Utilising one laser, it efficiently performs multi-parameter measurements, surpassing traditional flow cytometers  while incorporating the essential functions of immune analysers.

 

Challenges
  • IBS-D affects 10–20% of the global population and significantly reduces the quality of life
  • Conventional Western treatments focus on transient symptom control, often resulting in limited efficacy and high recurrence
  • Long-term pharmacological management is associated with side effects and poor patient compliance 

 

Breakthrough Technology
  • Optimised from a classical Chinese medicine prescription using evidence-based pharmacological and clinical research
  • Multi-target, multi-pathway mechanism regulating intestinal motility and inflammation, while alleviating visceral hypersensitivity via a novel butyrate-producing pathway
  • Proven symptom improvement after 8 weeks of treatment with sustained effects remaining even after discontinuation
  • Patented formulation with regulatory approval for clinical trials in both Hong Kong and the Chinese Mainland

 

Sequential Measurement Based Multi-Parameter Microfluidic Flow Cytomolecular Analyser Sequential Measurement Based Multi-Parameter Microfluidic Flow Cytomolecular Analyser
Figure 1: Schematic diagram of the detection workflow of the microfluidic flow cytomolecular analyser
Sequential Measurement Based Multi-Parameter Microfluidic Flow Cytomolecular Analyser Sequential Measurement Based Multi-Parameter Microfluidic Flow Cytomolecular Analyser
Figure 2: Prototype appearance of the microfluidic flow cytomolecular analyser
Sequential Measurement Based Multi-Parameter Microfluidic Flow Cytomolecular Analyser Sequential Measurement Based Multi-Parameter Microfluidic Flow Cytomolecular Analyser
Industry Applications
  • Gastrointestinal therapeutics
  • Preventive and integrative medicine
  • Chinese medicine based drug development
  • Hospital, outpatient and primary care IBS management 

 

Business Benefits
  • Large and growing IBS patient market with unmet clinical needs
  • Patented formulation with strong IP protection
  • Lower recurrence enhances long term patient retention
  • Strong commercialisation potential via licensing to pharmaceutical companies
Technology Readiness Level 8-9: System Test, Launch & Operations Technology Readiness Level 8-9: System Test, Launch & Operations
Team Leader

Professor Lei Bo, Adjunct Professor Department of Chemistry

Interested in Our Innovation?

Contact us at iit@hkbu.edu.hk to explore collaboration and partnership opportunities.